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Dec 11, 2017

Enbrel’s First Outcomes Contract is with Harvard Pilgrim; Others May Follow

Amgen is seeking additional outcomes-based contracts in rheumatoid arthritis through collaboration with Inovalon/Avalere.

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Dec 11, 2017

WAC-A-MOL

While investors, media and even some payers have been touting the pricing of three recently launched drugs as sensible, it is not clear whether the lower-than-expected list prices will actually reduce costs to payers. But they are likely to result in lower co-pays for patients, which could increase access.

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Dec 11, 2017

Can Cholesterol Drug Sponsors Make the Case for Statin Intolerance?

Amgen's FOURIER outcomes study of Repatha supports LDL-lowering in high risk patients, but price may have to come down dramatically to spur wide use of the PCSK9 inhibitors with the subjective condition of statin intolerance.

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Dec 11, 2017

Few Clouds On High-Priced, Ultra-Orphan Drug Horizon

With BioMarin's Brineura hitting the market with a $702,000 annual price tag, recent experience for other high-priced rare disease drugs supports the theory that payers will accept high costs for ultra-rare pediatric disease therapies.

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Dec 11, 2017

Entresto Facing Pressure From Diabetes Drugs

With diabetes therapeutics adding cardiovascular risk reduction claims, Novartis’s heart failure drug Entresto could face pressure from new fronts –

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Dec 11, 2017

Novartis’s Entresto Voyage: Hindsight is 20/20

What caused Novartis's innovative heart failure drug to falter, missing sales targets by $30m in 2016, and how is it expected to bounce back in 2017? Scrip explores Entresto's journey and what this experience shows about the changing face of pharma's customers.

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Dec 11, 2017

Why Drugmakers Aren’t Sweating the Next Wave of Patent Losses

Drugmakers plunged off a patent cliff earlier this decade, losing billions in sales as lucrative branded drugs lost exclusivity. An expensive lobbying effort aimed at preventing a repeat is paying off.

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Dec 11, 2017

Proving the Value of Value-Based Deals

As controversy continues over pharmaceutical pricing, more drugmakers are eyeing deals that peg health plan cost to outcomes to boost volume and win formulary placement. But these deals are challenging to construct and to date there is little evidence that they reduce costs for patients.

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