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Dec 12, 2017

Gilead Sees Prospects For Declining HCV Revenues To Stabilize

A confluence of factors, including a higher proportion of patients covered by public payers, has caused Gilead's powerhouse hepatitis C franchise to slow down and now begin showing signs of decline.

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Dec 12, 2017

Will Real-World Data Sway Course Of Novel Anticoagulant Market?

A wave of data to support use of novel anticoagulants in real-world settings was presented at the European Society of Cardiology Congress, but the question is whether this will alter the course of the market still dominated by warfarin and trailed by J&J/Bayer's Xarelto.

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Dec 12, 2017

Indication-Based Pricing Could Be Windfall for Interleukin Inhibitors

Express Scripts' plan to reimburse at levels according to value of specific indications in inflammatory diseases will create more space for new entrants with proven value.

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Dec 12, 2017

Getting Ahead of Headache

How Anti-CGRP mABs may fare in the migraine prevention space

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Dec 12, 2017

As Drug Value Frameworks Gain Traction, Patients Seek More Input

‘Patients are ready and willing to have conversations’ about trade-offs, National Health Council’s Perfetto says.

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Dec 12, 2017

Long-acting PCSK9 from Alnylam, TMC heads for PhIII, But Safety Spooks Investors

This past Christmas weekend, Ana Memedovich had her best two days in more than a decade. Her 23-year-old son Mikhail has spinal muscular atrophy, or SMA, a rare genetic disease that has slowly robbed him of the ability to walk and function independently.

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Dec 12, 2017

Value Tools Not in the Insurer Toolkit – Yet

Current versions by ASCO, NCCN, and others may not be right for insurers, but they are eyeing new ways to crunch the numbers for cost and outcomes.

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Dec 12, 2017

Drug Pricing: With “Value” Debate In Full Swing, ICER’s Influence Grows

The Institute for Clinical and Economic Review has invited feedback on its methodology for calculating a drug's recommended price range. Industry response has been critical, but pharma can no longer afford to merely oppose value frameworks. It needs to create strategies for a world in which such frameworks are a permanent and influential part of the pricing and reimbursement landscape.

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Dec 12, 2017

Can Slow Selling Heart Drug Entresto Perk Up in 2017? Novarits Hopes So

Sales of Novartis' Entresto have been painfully slow and missed their 2016 target of $200m – but the big pharma hopes the heart failure drug's sales momentum will take off next year and it remains confident the first-in-class therapy will eventually reach peak annual sales of around $5bn.

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Dec 12, 2017

Lawyers, Drugs and Money

Post-FOURIER: what Amgen needs to do to improve Repatha reimbursement.

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